The degree of interpatient variability in the warfarin dose required to achieve the desired anticoagulant response can only partly be explained by polymorphisms in the CYP2C9 gene, suggesting that additional genetic factors such as polymorphisms in genes involved in blood coagulation may influence warfarin dose requirement...
Keywords: Polymorphism, warfarin, cytochrome P450 2C9, pharmacodynamic factors, regression model
05/2006 | Thrombosis and Haemostasis, SchattauerEmerging findings have demonstrated the critical role of blood clotting factors in the formation and stabilization of embryonic blood vessels...
Keywords: Angiogenesis, warfarin, hirudin, heparin, Anticoagulant
07/2006 | Thrombosis and Haemostasis, SchattauerPatients with antiphospholipid antibody syndrome (APA) are at elevated risk of venous and arterial thromboembolic complications...
Keywords: warfarin, antiphospholipid antibody syndrome, thrombosis, anticoagulation clinic
08/2006 | Thrombosis and Haemostasis, Schattauer