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Items for "warfarin"

The influence of sequence variations in factor VII, -glutamyl carboxylase and vitamin K epoxide reductase complex genes on warfarin dose requirement

The degree of interpatient variability in the warfarin dose required to achieve the desired anticoagulant response can only partly be explained by polymorphisms in the CYP2C9 gene, suggesting that additional genetic factors such as polymorphisms in genes involved in blood coagulation may influence warfarin dose requirement...

Keywords: Polymorphism, warfarin, cytochrome P450 2C9, pharmacodynamic factors, regression model

05/2006 | Thrombosis and Haemostasis, Schattauer
Early in vivo anticoagulation inhibits the angiogenic response following hindlimb ischemia in a rodent model

Emerging findings have demonstrated the critical role of blood clotting factors in the formation and stabilization of embryonic blood vessels...

Keywords: Angiogenesis, warfarin, hirudin, heparin, Anticoagulant

07/2006 | Thrombosis and Haemostasis, Schattauer
Warfarin-related outcomes in patients with antiphospholipid antibody syndrome managed in an anticoagulation clinic

Patients with antiphospholipid antibody syndrome (APA) are at elevated risk of venous and arterial thromboembolic complications...

Keywords: warfarin, antiphospholipid antibody syndrome, thrombosis, anticoagulation clinic

08/2006 | Thrombosis and Haemostasis, Schattauer