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Items for "VWF"

A common origin of the 4143insA ADAMTS13 mutation

Severely deficient activity of the von Willebrand Factor (VWF) cleaving metalloprotease, ADAMTS13, is associated with thrombotic thrombocytopenic purpura (TTP)...

Keywords: ADAMTS13, TTP, VWF, mutation

07/2006 | Thrombosis and Haemostasis, Schattauer
ADAMTS-13 regulates platelet adhesion under flow. A new method for differentiation between inherited and acquired thrombotic thrombocytopenic purpura

ADAMTS-13 cleaves large and ultra-large von Willebrand factor multimers normally secreted by endothelial cells...

Keywords: ADAMTS-13, TTP, VWF, Impact-R

08/2006 | Thrombosis and Haemostasis, Schattauer