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Venous thrombosis
Items for "Venous thrombosis"
Idiopathic venous thrombosis. Long-term anticoagulant therapy? No
Venous thrombosis is a chronic disease with a recurrence rate of approximately 30% within 5-8 years. The optimal duration of secondary thromboprophylaxis in these patients entails balancing the risk of recurrence against the risk of treatment-associated bleeding...
Keywords: Venöse Thrombose, Rezidiv, sekundäre Thromboseprophylaxe, Vitamin-K-Antagonisten, Risikofaktoren
01/2006 | Hämostaseologie, SchattauerThrombophilia and pregnancy complications
Venous thromboembolism is the leading cause of pregnancy-associated morbidity and mortality. Women with thrombophilia have an increased risk of VTE in pregnancy and puerperium...
Keywords: Thrombophilie, Venöse Thrombose, Schwangerschaft, Abort, Präeklampsie
01/2006 | Hämostaseologie, SchattauerHaplotypes encoding the factor VIII 1241 Glu variation, factor VIII levels and the risk of venous thrombosis
Levels of factor VIII (FVIII) are associated with the risk of venous thrombosis. The FVIII variation D1241E has been reported to be associated with decreased levels of FVIII...
Keywords: FVIII, haplotypes, levels, Venous thrombosis, risk
06/2006 | Thrombosis and Haemostasis, SchattauerComparison of three activated protein C resistance tests in the risk assessment of venous thrombosis in non-carriers of the factor V Leiden mutation
Activated protein C resistance (APCR), measured using the original assay described by Dahlbck, is a risk factor for venous thrombosis independent of the factor V Leiden (FVL) mutation...
Keywords: Venous thrombosis, activated protein C resistance, factor V Leiden, factor VIII
04/2006 | Thrombosis and Haemostasis, SchattauerInterleukin-6 and interleukin-6 promoter polymorphism (174) G > C in patients with spontaneous venous thromboembolism
Increased levels of interleukin-6 (IL-6) have been reported in patients with a history of venous thromboembolism (VTE); however, prospective studies did not confirm an association between inflammatory markers that are highly correlated with IL-6 and the risk ofVTE...
Keywords: Interleukin-6, interleukin-6 promoter polymorphism, pulmonary embolism, Venous thrombosis
05/2006 | Thrombosis and Haemostasis, SchattauerAntithrombotic properties of Ixolaris, a potent inhibitor of the extrinsic pathway of the coagulation cascade
Ixolaris is a two-Kunitz tick salivary gland protein identified in Ixodes scapularis that presents extensive sequence homology to TFPI...
Keywords: Anticoagulant, ixolaris, Venous thrombosis, factor Xa, Tissue factor, tick saliva, Ixodes scapularis
07/2006 | Thrombosis and Haemostasis, SchattauerFactor V Leiden mutation and pregnancy-related venous thromboembolism: What is the exact risk? Results from a meta-analysis
The magnitude of the association of factor V Leiden mutation with pregnancy-related venous thrombosis remains unclear...
Keywords: Factor V Leiden mutation, Venous thrombosis, pregnancy, metaanalysis
07/2006 | Thrombosis and Haemostasis, SchattauerLow fasting methionine concentration as a novel risk factor for recurrent venous thrombosis
Hyperhomocysteinemia is a risk factor for venous thrombosis, but the underlying mechanism is unclear...
Keywords: Methionine, homocysteine, cysteine, Venous thrombosis
10/2006 | Thrombosis and Haemostasis, SchattauerImmunohistochemistry of thrombi following iliac venous stenting: A novel model of venous thrombosis
Stenting has become a common intervention for venous occlusive disease. Little is known regarding the composition of venous thrombi complicating stent placement...
Keywords: Venous thrombosis, vascular stents, platelets
11/2006 | Thrombosis and Haemostasis, SchattauerOvarian vein thrombosis: Incidence of recurrent venous thromboembolism and survival
For patients with ovarian vein thrombosis (OVT), neither the rate of recurrence nor the expected survival are well established...
Keywords: Ovarian vein, Venous thrombosis, hormones
08/2006 | Thrombosis and Haemostasis, SchattauerSELDI-TOF plasma profiles distinguish individuals in a protein C-deficient family with thrombotic episodes occuring before age 40
We tested the hypothesis that differences in the low-molecular-weight (500-20,000 Da) proteomic profile of plasma may be detectable between members of a protein C-deficient family who have suffered thrombotic events before age 40 compared to family members without a history of venous thrombosis...
Keywords: Venous thrombosis, SELDI-TOF, Mass spectrometry, proteomics, protein C deficiency
12/2006 | Thrombosis and Haemostasis, SchattauerIncidence of venous thromboembolism in first-degree relatives of patients with venous thromboembolism who have factor V Leiden
The factor V Leiden (FVL) mutation, a genetic abnormality with an autosomal mode of inheritance, is associated with an increased risk of venous thromboembolism (VTE)...
Keywords: Familial thrombosis, Venous thrombosis, factor V Leiden
12/2006 | Thrombosis and Haemostasis, SchattauerPrevention and treatment of experimental thrombosis in rabbits with rivaroxaban (BAY 597939) an oral, direct factor Xa inhibitor
Current anticoagulant therapies for the prevention and treatment of thromboembolic disorders have many drawbacks: vitamin K antagonists interact with food and drugs and require frequent laboratory monitoring, and heparins require parenteral administration...
Keywords: Factor Xa inhibitor, Venous thrombosis, prophylaxis, rivaroxaban, oral anticoagulant
03/2007 | Thrombosis and Haemostasis, SchattauerThe management of thrombosis in pregnancy: Role of low-molecular-weight heparin
Fatal pulmonary embolism remains the most common cause of mortality among pregnant women in many Western countries...
Keywords: pregnancy, Low-molecular-weight heparin, Thrombophilia, Venous thrombosis
04/2007 | Thrombosis and Haemostasis, SchattauerPlasma homocysteine cutoff values for venous thrombosis
Keywords: cutoff values, hyperhomocysteinemia, Venous thrombosis
02/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter