Items for "VASP phosphorylation"

Comparison of VASP-phosphorylation assay to light-transmission aggregometry in assessing inhibition of the platelet ADP P2Y 12 receptor

There is need to improve platelet function testing to monitor the response to antiplatelet drugs. We compared flow-cytometric analysis of intraplatelet vasodilator-stimulated phosphoprotein phosphorylation (VASP-P) to light-transmission aggregometry for the detection of drug-induced in-vitro inhibition of the platelet P2Y 12 ADP receptor on 22 healthy subjects (10 males, 12 females, 28.5 6.6 years)...

Keywords: VASP phosphorylation, platelet aggregation, P2Y12 ADP receptor antagonist, cangrelor