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Items for "urokinase"

High urokinase expression contributes to the angiogenic properties of endothelial cells derived from circulating progenitors

Endothelial progenitor cells (EPC) display a unique ability to repair vascular injury and promote neovascularization although the underlying molecular mechanisms remain poorly understood...

Keywords: Endothelial progenitor, urokinase, Angiogenesis, proteolysis

04/2006 | Thrombosis and Haemostasis, Schattauer
Disease processes may be reflected by correlations among tissue kallikrein proteases but not with proteolytic factors uPA and PAI-1 in primary ovarian carcinoma

In epithelial ovarian cancer, the high mortality rate is usually ascribed to late diagnosis, since these tumors commonly lack early-warning symptoms, but tumor-associated biomarkers useful for prognosis or therapy response prediction are in short supply...

Keywords: ovarian cancer, PAI-1, plasminogen activator, plasminogen activator inhibitor type-1, proteolytic factors, tissue kallikreins, uPA, urokinase

08/2006 | Biological Chemistry, Walter de Gruyter