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Items for "tyrosinase"

Evidence for a common regulation in the activation of a polyphenol oxidase by trypsin and sodium dodecyl sulfate

Polyphenol oxidase (PPO) was extracted from beet root, in both soluble and membrane fractions, and in both cases the enzyme was in a latent state...

Keywords: Beta vulgaris, betalains, latency, proteolysis, tyrosinase

06/2005 | Biological Chemistry, Walter de Gruyter
Molecular detection of tyrosinase transcripts in peripheral blood from patients with malignant melanoma: correlation of PCR sensitivity threshold with clinical and pathologic disease characteristics

Background: Positive molecular detection of tyrosinase transcripts (TYR mRNA) in RNA extracts of peripheral blood (PB) samples from patients with malignant melanoma provides evidence of disease dissemination.

Methods: Total RNA extracted from PB was quantified and subjected to RT-PCR under ultra-sensitive and reduced-sensitivity PCR conditions using SSRT-II...

Keywords: Malignant melanoma, mRNA, peripheral, polymerase chain reaction, tyrosinase

12/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
The effect of chlorophorin and its derivative on melanin biosynthesis

By means of bioassay-guided fractionation using mushroom tyrosinase, a geranylated stilbene, chlorophorin, was characterized as the principal tyrosinase inhibitor in the heartwood of Chlorophora excelsa (Moraceae)...

Keywords: Chlorophora excelsa, chlorophorin, hexahydrochlorophorin, melanin, Moraceae, tyrosinase

09/2005 | Holzforschung, Walter de Gruyter