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Items for "TRPs"

Bradykinin and peripheral sensitization

Pain hypersensitivity after tissue injury and inflammation is contributed to by a reduction in the threshold and an increase in the responsiveness of the peripheral terminals of high-threshold nociceptor neurons, the phenomenon of peripheral sensitization...

Keywords: bradykinin, ion channels, nociceptors, pain hypersensitivity, peripheral sensitization, TRPs

01/2006 | Biological Chemistry, Walter de Gruyter
SUMOylation modulates transcriptional repression by TRPS1

Mutations or deletions of the TRPS1 gene on human chromosome 8q.24.1 cause the tricho-rhino-phalangeal syndromes (TRPS), which are characterized by craniofacial and skeletal malformations...

Keywords: GATA, posttranslational modification, repression domain, SUMO, TRPs, UBC9

04/2007 | Biological Chemistry, Walter de Gruyter