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Items for "Transgenic animals"

Tolerance to factor VIII in a transgenic mouse expressing human factor VIII cDNA carrying an Arg593 to Cys substitution

Inhibitory antibodies develop in approximately 25% of patients with severe hemophilia. A following treatment with factorVIII...

Keywords: Transgenic animals, haemophilia A / B, factor VIII

00/0000 | Thrombosis and Haemostasis, Schattauer
Genetically altered animal models in the kallikrein-kinin system

Transgenic and gene-targeting technologies allowing the generation of genetically altered animal models have greatly advanced our understanding of the function of specific genes...

Keywords: bradykinin, kininase, kininogen, kinin receptor, knockout animals, Transgenic animals

02/2006 | Biological Chemistry, Walter de Gruyter