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Items for "Transcriptome"

Deconfounding Microarray Analysis Independent Measurements of Cell Type Proportions Used in a Regression Model to Resolve Tissue Heterogeneity Bias

OBJECTIVES: Microarray analysis requires standardized specimens and evaluation procedures to achieve acceptable results...

Keywords: Transcriptome, tissue heterogeneity, deconfounding

01/2006 | Methods of Information in Medicine, Schattauer

Analysis of SAGE data in human platelets: Features of the transcriptome in an anucleate cell

A comprehensive SAGE (serial analysis of gene expression) library of purified human platelets was established...

Keywords: Platelet, Transcriptome, SAGE, signaling pathway, post-transcriptional regulation, RNA element, Gene Ontology

04/2006 | Thrombosis and Haemostasis, Schattauer

Kallikrein-related peptidase (KLK) family mRNA variants and protein isoforms in hormone-related cancers: do they have a function?

The kallikrein-related peptidase (KLK) gene family of 15 serine proteases encodes many proteins, including prostate specific antigen (PSA or KLK3), that are well described and/or are potential biomarkers for hormone-related cancers...

Keywords: mRNA splicing, nuclear localisation, serine protease, Transcriptome

06/2006 | Biological Chemistry, Walter de Gruyter

Transcriptional responses of Plasmodium falciparum to ?-difluoromethylornithine-induced polyamine depletion

Polyamines are essential polycationic molecules involved in multiple cellular events, including cell differentiation, division and death...

Keywords: malaria, microarray, suppression subtractive hybridisation, Transcriptome