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Items for "transcription"

GRIP1 mediates the interaction between the amino- and carboxyl-termini of the androgen receptor

The androgen receptor (AR) mediates transactivation of target genes by acting as a dimer in which its amino-terminal domain (AR-NTD) interacts with its carboxyl-terminal, ligand-binding domain (AR-LBD) (N/C interaction)...

Keywords: androgen receptor, coactivator, dimerization, domain interactions, transactivation, transcription

01/2005 | Biological Chemistry, Walter de Gruyter
Varicella-zoster virus IE63 protein represses the basal transcription machinery by disorganizing the pre-initiation complex

Using transient transfection assays, regulation properties of varicella-zoster virus (VZV)-encoded IE63 protein were analyzed on several VZV immediate early (ORF4), early (ORF28) and late (ORF67) promoters...

Keywords: down-regulation, general transcription factors, repression, transcription, varicella-zoster

03/2005 | Biological Chemistry, Walter de Gruyter
Dynamic chromatin: concerted nucleosome remodelling and acetylation

The flexibility of chromatin that enables translation of environmental cues into changes in genome utilisation, relies on a battery of enzymes able to modulate chromatin structure in a highly targeted and regulated manner...

Keywords: ATPase, HAT, histone modification, repair, transcription

08/2005 | Biological Chemistry, Walter de Gruyter
Rec A-independent homologous recombination induced by a putative fold-back tetraplex DNA

We have recently reported that a GC-rich palindromic repeat sequence presumably adopts a stable fold-back tetraplex DNA structure under supercoiling...

Keywords: fold-back tetraplex, homologous recombination, palindrome, RecA, transcription

03/2006 | Biological Chemistry, Walter de Gruyter
The zinc finger protein ZNF297B interacts with BDP1, a subunit of TFIIIB

The human gene BDP1, localized on chromosome 5q13 in close proximity to the spinal muscular atrophy determining gene SMN, encodes a large protein consisting of 2254 amino acids (aa)...

Keywords: SMA, TFNR, transcription, yeast two-hybrid, ZNF-X

03/2006 | Biological Chemistry, Walter de Gruyter
Impaired synthesis of heme oxygenase-1 in Fanconi anemia cells can be rescued by transfection of Fanconi wild-type cDNA

Fanconi anemia is a fatal, hereditary chromosome instability syndrome of early childhood with progressive pancytopenia and cancer-proneness...

Keywords: antioxidative defense, BRCA1, Gene expression, reactive oxygen intermediates, thioredoxin, transcription

10/2008 | Biological Chemistry, Walter de Gruyter
The role of long non-coding RNAs in chromatin structure and gene regulation: variations on a theme

Transcriptome studies have uncovered a plethora of non-coding RNAs (ncRNA) in mammals...

Keywords: histone modifications, nuclear organization, transcription, transcription factories

04/2008 | Biological Chemistry, Walter de Gruyter
Transcriptions and ISO 15189

No available

Keywords: accreditation, standard ISO 15189, subcontracting, transcription

07/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter