The androgen receptor (AR) mediates transactivation of target genes by acting as a dimer in which its amino-terminal domain (AR-NTD) interacts with its carboxyl-terminal, ligand-binding domain (AR-LBD) (N/C interaction)...
Keywords: androgen receptor, coactivator, dimerization, domain interactions, transactivation, transcription
01/2005 | Biological Chemistry, Walter de GruyterUsing transient transfection assays, regulation properties of varicella-zoster virus (VZV)-encoded IE63 protein were analyzed on several VZV immediate early (ORF4), early (ORF28) and late (ORF67) promoters...
Keywords: down-regulation, general transcription factors, repression, transcription, varicella-zoster
03/2005 | Biological Chemistry, Walter de GruyterThe flexibility of chromatin that enables translation of environmental cues into changes in genome utilisation, relies on a battery of enzymes able to modulate chromatin structure in a highly targeted and regulated manner...
Keywords: ATPase, HAT, histone modification, repair, transcription
08/2005 | Biological Chemistry, Walter de GruyterWe have recently reported that a GC-rich palindromic repeat sequence presumably adopts a stable fold-back tetraplex DNA structure under supercoiling...
Keywords: fold-back tetraplex, homologous recombination, palindrome, RecA, transcription
03/2006 | Biological Chemistry, Walter de GruyterThe human gene
Keywords: SMA, TFNR, transcription, yeast two-hybrid, ZNF-X
03/2006 | Biological Chemistry, Walter de GruyterFanconi anemia is a fatal, hereditary chromosome instability syndrome of early childhood with progressive pancytopenia and cancer-proneness...
Keywords: antioxidative defense, BRCA1, Gene expression, reactive oxygen intermediates, thioredoxin, transcription
10/2008 | Biological Chemistry, Walter de GruyterTranscriptome studies have uncovered a plethora of non-coding RNAs (ncRNA) in mammals...
Keywords: histone modifications, nuclear organization, transcription, transcription factories
04/2008 | Biological Chemistry, Walter de GruyterNo available
Keywords: accreditation, standard ISO 15189, subcontracting, transcription
07/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter