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Items for "tocolysis"

Feasibility of a randomized controlled trial testing nifedipine vs. placebo for the treatment of preterm labor

Aims: Nifedipine is believed to be a superior tocolytic agent on the basis of efficacy and side-effect profile, but was never prospectively evaluated in a placebo-controlled randomized clinical trial (RCT)...

Keywords: Feasibility study, nifedipine, preterm labor, randomized controlled trial, tocolysis

04/2007 | Journal of Perinatal Medicine, Walter de Gruyter
Atosiban versus usual care for the management of preterm labor

Objective: To compare the efficacy of atosiban with usual management of threatened preterm labor.

Methods: In this prospective, open-label, randomized controlled trial, women admitted to the hospital in threatened preterm labor (between 24 and 34 weeks' gestation) were randomized to receive atosiban or usual care (?-agonists, calcium channel blockers, magnesium sulphate, or any other tocolytic, alone or in combination, and/or bed rest).

Results: In women randomized to receive atosiban (n=295) or usual care (n=290), significantly more women receiving atosiban remained undelivered at 48 h with no alternative tocolytic compared with usual care (77.6% vs...

Keywords: Atosiban, preterm labor, tocolysis, tocolytic therapy

08/2007 | Journal of Perinatal Medicine, Walter de Gruyter
Negative fetal fibronectin: Who is still treating for threatened preterm labor and does it help?

Objective: Fetal fibronectin (fFN) has a high negative predictive value for delivery in the next seven days in patients at risk for preterm birth...

Keywords: fetal fibronectin, preterm birth, tocolysis

05/2008 | Journal of Perinatal Medicine, Walter de Gruyter