Aims: Nifedipine is believed to be a superior tocolytic agent on the basis of efficacy and side-effect profile, but was never prospectively evaluated in a placebo-controlled randomized clinical trial (RCT)...
Keywords: Feasibility study, nifedipine, preterm labor, randomized controlled trial, tocolysis
04/2007 | Journal of Perinatal Medicine, Walter de Gruyter
Objective: To compare the efficacy of atosiban with usual management of threatened preterm labor.
Methods: In this prospective, open-label, randomized controlled trial, women admitted to the hospital in threatened preterm labor (between 24 and 34 weeks' gestation) were randomized to receive atosiban or usual care (?-agonists, calcium channel blockers, magnesium sulphate, or any other tocolytic, alone or in combination, and/or bed rest).
Results: In women randomized to receive atosiban (n=295) or usual care (n=290), significantly more women receiving atosiban remained undelivered at 48 h with no alternative tocolytic compared with usual care (77.6% vs...
Keywords: Atosiban, preterm labor, tocolysis, tocolytic therapy
08/2007 | Journal of Perinatal Medicine, Walter de Gruyter
Objective: Fetal fibronectin (fFN) has a high negative predictive value for delivery in the next seven days in patients at risk for preterm birth...
Keywords: fetal fibronectin, preterm birth, tocolysis
05/2008 | Journal of Perinatal Medicine, Walter de Gruyter