In epithelial ovarian cancer, the high mortality rate is usually ascribed to late diagnosis, since these tumors commonly lack early-warning symptoms, but tumor-associated biomarkers useful for prognosis or therapy response prediction are in short supply...
Keywords: ovarian cancer, PAI-1, plasminogen activator, plasminogen activator inhibitor type-1, proteolytic factors, tissue kallikreins, uPA, urokinase
08/2006 | Biological Chemistry, Walter de GruyterHuman kallikrein-related peptidase 12 (KLK12) is a new member of the human tissue kallikrein family...
Keywords: enzyme activity, enzyme cascades, serine proteases, tissue kallikreins, trypsin-like activity, tumor markers
04/2007 | Biological Chemistry, Walter de Gruyter