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Items for "tissue kallikreins"

Disease processes may be reflected by correlations among tissue kallikrein proteases but not with proteolytic factors uPA and PAI-1 in primary ovarian carcinoma

In epithelial ovarian cancer, the high mortality rate is usually ascribed to late diagnosis, since these tumors commonly lack early-warning symptoms, but tumor-associated biomarkers useful for prognosis or therapy response prediction are in short supply...

Keywords: ovarian cancer, PAI-1, plasminogen activator, plasminogen activator inhibitor type-1, proteolytic factors, tissue kallikreins, uPA, urokinase

08/2006 | Biological Chemistry, Walter de Gruyter
Enzymatic properties of human kallikrein-related peptidase 12 (KLK12)

Human kallikrein-related peptidase 12 (KLK12) is a new member of the human tissue kallikrein family...

Keywords: enzyme activity, enzyme cascades, serine proteases, tissue kallikreins, trypsin-like activity, tumor markers

04/2007 | Biological Chemistry, Walter de Gruyter