Items for "Tiam1"

p190-RhoGAP as an integral component of the Tiam1/Rac1-induced downregulation of Rho

The Rho family of small GTPases plays a central role in intracellular signal transduction, particularly in reorganization of the actin cytoskeleton...

Keywords: GTPase, p115-RhoGEF, p190-RhoGAP, PDZ-RhoGEF, Rac, Rho, Tiam1