Aim of our study was to evaluate the increasing sensitivity within three generations of thyroglobulin (Tg) assays, which were available during the past decade, and its clinical impact for patients with differentiated thyroid carcinoma. METHODS: Determination of Tg using the IRMA introduced in 1989 (DynotestTg, Henning Berlin, Berlin; assay A) and 1994 (Selco Tg, Medipan Diagnostica, Selchow; assay B), as well as the IEMA available recently (MedizymTg Rem, Medipan Diagnostica, Selchow; assay C). RESULTS: We found a close correlation between the measurable Tg values of assay A and B (r=0.985; p<0.001) as well as assay B and C (r=0.978; p<0.001)...
Keywords: Thyreoglobulinbestimmung, Tg-Assay, IRMA, IEMA, Schilddrüsenkarzinom
01/2003 | Nuklearmedizin, SchattauerAIM: The Multicenter Study Differentiated Thyroid Carcinoma (MSDS) is an ongoing study in Germany, Austria, and Switzerland on the clinical benefit of adjuvant external beam radiotherapy (RTx) for locally invasive differentiated thyroid carcinoma (DTC) in TNM stages pT4 pN0/1/x M0/x (5th ed...
Keywords: Schilddrüsenkarzinom, Strahlentherapie, randomisierte Studie, Radioiod, Thyreoidektomie
01/2003 | Nuklearmedizin, SchattauerAim: The lately updated German guideline on radiation protection in medicine (Richtlinie Strahlenschutz in der Medizin) requires the physician who administers radioactive substances for therapy, to perform and document follow-ups...
Keywords: Schilddrüsenkarzinom, Radioiodtherapie, Behandlungskontrolle, Nachsorge
01/2005 | Nuklearmedizin, SchattauerAim: For the examination of the impact on clinical practice of the guidelines for differentiated thyroid carcinoma (DTC), treatment data from the ongoing Multicenter Study Differentiated Thyroid Carcinoma (MSDS) were analyzed...
Keywords: Schilddrüsenkarzinom, klinische Leitlinien, Radioiodtherapie, Iod-131
01/2005 | Nuklearmedizin, SchattauerAim: Urinary iodine excretion (UIE) provides information about iodine supply and release. In the present study we investigated effects of the application of different radioiodine isotopes on UIE in patients with differentiated thyroid carcinoma (DTC)...
Keywords: Schilddrüsenkarzinom, Radioiod-Szintigraphie, Radioiodtherapie, Uriniodausscheidun
01/2005 | Nuklearmedizin, SchattauerBackground: Thyroidectomy followed by administration of large activities of 131I is the treatment of choice for differentiated thyroid carcinomas...
Keywords: radioiodine, thyroglobulin, thyroid carcinoma, thyroidectomy, tumour marker
08/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter