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Items for "thyroid antibodies"

The effect of thyroid antibody positivity on reference intervals for thyroid stimulating hormone (TSH) and free thyroxine (FT4) in an aged population

Our aims were: 1) to analyze the effect of the methodology used to derive clinically feasible cut-off values for thyroid peroxidase antibodies (TPOAb) and thyroglobulin antibodies (TgAb), which exhibit highly skewed distributions; and 2) to describe the influence of thyroid antibodies on thyroid stimulating hormone (TSH) and free thyroxine (FT4) reference intervals among thyroid disease-free aged subjects...

Keywords: aged, hypothyroidism, reference interval, thyroid antibodies, thyroid function tests

12/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Establishment of reference distributions and decision values for thyroid antibodies against thyroid peroxidase (TPOAb), thyroglobulin (TgAb) and the thyrotropin receptor (TRAb)

Background: The National Academy of Clinical Biochemistry (NACB) stresses that the reference intervals for thyroid peroxidase antibodies (TPOAb), thyroglobulin antibodies (TgAb) and thyroid stimulating hormone (TSH)-receptor antibodies (TRAb) should be based on young men who lack certain risk factors and have serum TSH between 0.5 and 2.0 mIU/L...

Keywords: composite distributions, ln-Gaussian distributions, models, NACB guidelines, rankit plot, reference interval, thyroid antibodies, thyroid hormones

08/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter