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Items for "thrombotic thrombocytopenic purpura"

ADAMTS13-binding IgG are present in patients with thrombotic thrombocytopenic purpura

Functional assays are commonly used to measure the antibodies of ADAMTS13 found in patients of thrombotic thrombocytopenic purpura (TTP)...

Keywords: ADAMTS13, thrombotic thrombocytopenic purpura, antibody

05/2006 | Thrombosis and Haemostasis, Schattauer

Amino acid regions 572579 and 657666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP

Antibodies directed against ADAMTS13 have been detected in the majority of patients with acquired thrombotic thrombocytopenic purpura (TTP)...

Keywords: ADAMS/ADAMTS 13, autoantibodies, thrombotic thrombocytopenic purpura, TTP, HUS

09/2006 | Thrombosis and Haemostasis, Schattauer

In-vitro and in-vivo consequences of mutations in the von Willebrand factor cleaving protease ADAMTS13 in thrombotic thrombocytopenic purpura

Thrombotic thrombocytopenic purpura (TTP) is a disease characterized by microvascular thrombosis, often associated with deficiency of the vonWillebrand factor (VWF) cleaving protease ADAMTS13...

Keywords: thrombotic thrombocytopenic purpura, ADAMTS13, mutations, expression studies

10/2006 | Thrombosis and Haemostasis, Schattauer

Von Willebrand Faktor spaltende Protease und thrombotische Mikroangiopathien. Von Willebrand factor cleaving protease and thrombotic microangiopathy

Zusammenfassung

Zusammenfassung Die thrombotisch thrombozytopenische Purpura (TTP) ist durch das generalisierte Auftreten von hyalinen Thromben in der Mikrozirkulation gekennzeichnet...

Keywords: ADAMTS-13, thrombotisch thrombozytopenische Purpura, thrombotische Mikroangiopathie, VWF spaltende Protease, thrombotic microangiopathy, thrombotic thrombocytopenic purpura, VWF-cleaving protease