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Items for "thrombosis"

Alternatively spliced human tissue factor (asHTF) is not pro-coagulant

It has been proposed that alternatively-spliced human tissue factor (asHTF) is pro-coagulant. We have evaluated the function of asHTF in a mammalian expression system...

Keywords: Coagulation factors, tissue factor / factor VII, thrombosis

01/2007 | Thrombosis and Haemostasis, Schattauer

Pathophysiology of acute coronary syndrome

This article reviews the current understanding of the pathophysiology of acute coronary syndrome and how these concepts have altered our clinical approach to the acute phase of coronary heart disease...

Keywords: Akutes Koronarsyndrom, Plaqueruptur, Thrombose, Ischämie, Inflammation

01/2006 | Hämostaseologie, Schattauer

Serious complications after radiosynoviorthesis. Survey on frequency and treatment modalities

AIM: Radiosynoviorthesis using intraarticular injection of beta-emitting radiocolloids is increasingly performed throughout Europe in patients with inflammatory joint disease...

Keywords: Radiosynoviorthese, Synovalitis, Nekrose, Thrombose, Infektion

01/2006 | Nuklearmedizin, Schattauer

Thromboembolism risk reduction in multiple myeloma patients treated with immunomodulatory drug combinations

Deep vein thrombosis and its lethal complication pulmonary embolism are manifestations of venous thromboembolism (VTE), which is typically associated with cancer and recent major surgery...

Keywords: Multiple myeloma, thrombosis, anticoagulants, thalidomide, lenalidomide

06/2006 | Thrombosis and Haemostasis, Schattauer

Pharmacologic inhibition of platelet vWF-GPIb interaction prevents coronary artery thrombosis

Under high shear arterial blood flow von Willebrand Factor (vWF) binds the platelet receptor glycoprotein (GP) Ib, leading to platelet adhesion, activation and thrombosis...

Keywords: Glycoprotein (GP) Iba, platelet adhesion, platelet agglutination, thrombosis, von Willebrand factor (vWF)

03/2006 | Thrombosis and Haemostasis, Schattauer

Warm-up exercise suppresses platelet-eosinophil/neutrophil aggregation and platelet-promoted release of eosinophil/neutrophil oxidant products enhanced by severe exercise in men

Heterotypic platelet-eosinophil/neutrophil aggregation and subsequent release of eosinophil/neutrophil oxidant products contribute to pathogenesis of conditions such as asthma and inflammatory bowel diseases...

Keywords: Warm-up, eosinophil, Platelet, inflammation, thrombosis

03/2006 | Thrombosis and Haemostasis, Schattauer

Hyperprothrombinaemia-induced APC resistance: Differential influence on fibrin formation and fibrinolysis

The prothrombin gene mutation G20210A is a common risk factor for thrombosis and has been reported to cause APC resistance...

Keywords: Protein C, prothrombin G20210A, TAFI, thrombin generation, thrombosis

04/2006 | Thrombosis and Haemostasis, Schattauer

Thrombophilic risk factors and homocysteine levels in Behets disease in eastern Spain and their association with thrombotic events

Behets disease (BD) is a chronic inflammatory disorder in which thrombosis occurs in about 30% of patients...

Keywords: Behçet’s disease, hyperhomocysteinaemia, thrombophilic risk factors, thrombosis, meta-analysis

04/2006 | Thrombosis and Haemostasis, Schattauer

Local delivery of soluble platelet collagen receptor glycoprotein VI inhibits thrombus formation in vivo

Platelet-mediated thrombus formation at the site of vascular injury is a major trigger for thrombo-ischemic complications after coronary interventions...

Keywords: angioplasty, glycoprotein VI, platelets, thrombosis, collagen

05/2006 | Thrombosis and Haemostasis, Schattauer

In vivo antithrombotic synergy of oral heparin and arginine: Endothelial thromboresistance without changes in coagulation parameters

On the basis of suggested clinical efficacy in an uncontrolled study in ninety-seven patients with unstable angina, an animal study was conducted to investigate antithrombotic synergy between orally administered heparin and arginine...

Keywords: heparin, thrombosis, endothelium, arginine, oral

05/2006 | Thrombosis and Haemostasis, Schattauer

COX-2 inhibitors and cardiovascular risk. Inferences based on biology and clinical studies

Even though non-steroidal anti-inflammatory drugs (NSAIDs) have been widely used for a long time, the search continues for anti-inflammatory drugs with few side-effects...

Keywords: atherosclerosis, thrombosis, inflammation, hypercoagulability, coronary syndrome

10/2006 | Thrombosis and Haemostasis, Schattauer

The gender-specific role of polymorphisms from the fibrinolytic, renin-angiotensin, and bradykinin systems in determining plasma t-PA and PAI-1 levels

Tissue plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1) directly influence thrombus formation and degradation and thus risk for arterial thrombosis...

Keywords: epidemiological studies, thrombosis, risk factors, plasminogen, sex

10/2006 | Thrombosis and Haemostasis, Schattauer

Prevalence of thromboembolic events among 8,860 patients with thalassaemia major and intermedia in the Mediterranean area and Iran

Beta-thalassaemia is a congenital haemolytic anaemia characterized by partial (intermedia, TI) or complete (major, TM) deficiency in the production of -globin chains...

Keywords: thrombosis, thalassaemia intermedia, thalassaemia major

10/2006 | Thrombosis and Haemostasis, Schattauer

Warfarin-related outcomes in patients with antiphospholipid antibody syndrome managed in an anticoagulation clinic

Patients with antiphospholipid antibody syndrome (APA) are at elevated risk of venous and arterial thromboembolic complications...

Keywords: warfarin, antiphospholipid antibody syndrome, thrombosis, anticoagulation clinic

08/2006 | Thrombosis and Haemostasis, Schattauer

Focal arterial inflammation is augmented in mice with a deficiency of the protein C gene

Increased risk of thrombosis, with propitious conditions for fibrin deposition, along with upregulation of inflammation, are important factors that enhance plaque formation in atherosclerosis...

Keywords: inflammation, thrombosis, arterial injury, arterial remodeling, arterial neointima formation

12/2006 | Thrombosis and Haemostasis, Schattauer

Potent arterial antithrombotic effect of direct factor-Xa inhibition with ZK-807834 administered to coronary artery disease patients

It was the objective of this study to evaluate the anti-thrombotic potency of direct factor-Xa inhibition with ZK-807834 in stable coronary patients, using an ex-vivo model of arterial thrombus formation...

Keywords: Coagulation, Coronary disease, myocardial infarction, thrombosis, platelets

03/2007 | Thrombosis and Haemostasis, Schattauer

Incidence and distribution of lower extremity deep venous thrombosis at indirect computed tomography venography in patients suspected of pulmonary embolism

Indirect computed tomography (CT) venography reportedly provides high accuracy for detection of venous thrombosis in patients suspected of pulmonary embolism (PE)...

Keywords: pulmonary embolism, computed tomography (CT), venography, angiography, veins, thrombosis, thromboembolism

04/2007 | Thrombosis and Haemostasis, Schattauer

Active endothelin is an important vasoconstrictor in acute coronary thrombi

Acute coronary syndrome is characterized by compromised blood flow at the epicardial and microvascular levels...

Keywords: acute myocardial infarction, thrombosis, endothelin / -receptors, leukocyte function / activation, arterial thrombosis

04/2007 | Thrombosis and Haemostasis, Schattauer

Protein disulphide isomerase-mediated LA419 NO release provides additional antithrombotic effects to the blockade of the ADP receptor

Despite the proven efficacy of current antithrombotic therapy in preventing ischemic heart disease (IHD), vascular events still occur...

Keywords: thrombosis, platelets, nitric oxide

04/2007 | Thrombosis and Haemostasis, Schattauer

Rapid combined genotyping of factor V, prothrombin and methylenetetrahydrofolate reductase single nucleotide polymorphisms using minor groove binding DNA oligonucleotides (MGB probes) and real-time polymerase chain reaction

Risk factors for cardiovascular diseases and venous thromboembolism involve both acquired and hereditary conditions...

Keywords: minor groove binder, mutation detection, real-time polymerase chain reaction (PCR), single nucleotide polymorphism, thrombosis

12/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

In vitro inhibition of fibrinolysis by apolipoprotein(a) and lipoprotein(a) is size- and concentration-dependent

Lipoprotein(a) (Lp(a)) is considered an independent risk factor for atherosclerotic heart and circulatory diseases...

Keywords: fibrinolysis, inhibition, lipoprotein(a), Phenotype, thrombosis

09/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Dilatation of the abdominal umbilical vein is associated with increased risk of thrombotic complications

Malformations of the umbilical vein are rare abnormalities diagnosed on prenatal ultrasound...

Keywords: Aneurismatic dilatation, antithrombotic therapy, malformation, thrombosis, umbilical vein

05/2006 | Journal of Perinatal Medicine, Walter de Gruyter

Laboratory diagnosis and clinical manifestations of patients with dysfibrinogenemia / Laboratoriumsdiagnostik und klinische Manifestation der Dysfribrinogenämie

Hereditary dysfibrinogenemia is a rare clotting disorder due to a structural defect in the fibrinogen molecule that results in a tendency for bleeding and thrombosis, as well as obstetric complications...

Keywords: bleeding, dysfibrinogenemia, miscarriage, thrombosis, Abort, Blutung, Dysfibrinogenämia, Thrombose

11/2008 | LaboratoriumsMedizin, Walter de Gruyter

Hypochlorous acid is a potent inactivator of human plasminogen at concentrations secreted by activated granulocytes

Background: Myeloperoxidase (MPO) neutrophils have been considered an important pathophysiological factor in oxidative stress...

Keywords: atherosclerosis, Coagulation, myeloperoxidase, oxidative stress, Plasmin, thiols, thrombosis

10/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

Role for mitochondrial uncoupling protein-2 (UCP2) in hyperhomocysteinemia and venous thrombosis risk?

Background: Hyperhomocysteinemia has been associated with an increased risk of venous thrombosis, which might be mediated through an oxidative stress dependent mechanism...

Keywords: homocysteine, mitochondria, thrombosis, uncoupling protein-2

05/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

The molecular basis of homocysteine thiolactone-mediated vascular disease

Accumulating evidence suggests that a metabolite of homocysteine (Hcy), the thioester Hcy-thiolactone, plays an important role in atherogenesis and thrombosis...

Keywords: atherosclerosis, autoantibodies, cystathionine ?-synthase (CBS), dietary hyperhomocysteinemia, fibrinogen, genetic hyperhomocysteinemia, homocysteine thiolactone hypothesis, immune activation, methylenetetrahydrofolate reductase (MTHFR), protein N-homocysteinylation, thrombosis

12/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter

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You are here: Home :: Keyword index :: the bis Vie :: threshold scheme - thromboxane generation thrombosis

Items for "thrombosis"