The main structural feature of direct thrombin inhibitor LK-732 responsible for the appropriate interaction at the thrombin active site is a strong basic group...
Keywords: Thrombin inhibitors, azaphenylalanine scaffold, mast cell degranulation, basicity, rat
00/0000 | Thrombosis and Haemostasis, SchattauerThrombininhibitoren sind als Antikoagulans für spezielle Indikationen zur Therapie zugelassen...
Keywords: aktivierte partielle Thromboplastinzeit, chromogener Substrattest, Ecarin-Gerinnungszeit, therapeutisches Drugmonitoring, Thrombininhibitoren, activated partial thromboplastin time, chromogenic substrate assay, ecarin clotting time, therapeutic drug monitoring, Thrombin inhibitors
10/2006 | LaboratoriumsMedizin, Walter de Gruyter