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Items for "Thrombin inhibitors"

Direct thrombin inhibitors built on the azaphenylalanine scaffold provoke degranulation of mast cells

The main structural feature of direct thrombin inhibitor LK-732 responsible for the appropriate interaction at the thrombin active site is a strong basic group...

Keywords: Thrombin inhibitors, azaphenylalanine scaffold, mast cell degranulation, basicity, rat

00/0000 | Thrombosis and Haemostasis, Schattauer
Methoden zur Bestimmung von Thrombininhibitoren / Methods for the determination of thrombin inhibitors

Zusammenfassung

Thrombininhibitoren sind als Antikoagulans für spezielle Indikationen zur Therapie zugelassen...

Keywords: aktivierte partielle Thromboplastinzeit, chromogener Substrattest, Ecarin-Gerinnungszeit, therapeutisches Drugmonitoring, Thrombininhibitoren, activated partial thromboplastin time, chromogenic substrate assay, ecarin clotting time, therapeutic drug monitoring, Thrombin inhibitors

10/2006 | LaboratoriumsMedizin, Walter de Gruyter