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therapeutic drug monitoring
Items for "therapeutic drug monitoring"
A simple isocratic HPLC assay to determine linezolid concentrations in different biomatrices for in vivo and in vitro studies
Keywords: analytics, pharmacodynamics, pharmacokinetics, therapeutic drug monitoring, tissues
08/2007 | Clinical Chemical Laboratory Medicine, Walter de GruyterPharmacogenomics and adverse drug reactions in diagnostic and clinical practice
Pharmacogenetics and pharmacogenomics deal with genetically determined variations in how individuals respond to drugs...
Keywords: adverse drug reactions, CYP2D6, CYP2C9, CYP2C19, genetic polymorphism, pharmacogenetics, pharmacogenomics, therapeutic drug monitoring, thiopurine S-methyltransferase (TPMT), uridine diphosphate glucuronosyltransferase (UGT1A1)
07/2007 | Clinical Chemical Laboratory Medicine, Walter de GruyterTherapeutic monitoring of immunosuppressant drugs. Where are we?
The emergence of specific immunosuppressive drugs (cyclosporine, tacrolimus, mycophenolate mofetil and sirolimus) during the last two decades has contributed dramatically to the success of organ transplantation...
Keywords: cyclosporine, mycophenolic acid, sirolimus, tacrolimus, therapeutic drug monitoring
11/2004 | Clinical Chemical Laboratory Medicine, Walter de GruyterTherapeutic drug monitoring of non-tricyclic antidepressant drugs
Therapeutic drug monitoring (TDM) of many of the tricyclic antidepressants (TCAs) has been demonstrated to be of clear clinical value...
Keywords: cytochrome P450, non-tricyclic antidepressant, selective serotonin reuptake inhibitors (SSRIs), therapeutic drug monitoring, venlafaxine
11/2004 | Clinical Chemical Laboratory Medicine, Walter de GruyterTherapeutic drug monitoring of old and newer anti-epileptic drugs
The aim of the present paper is to provide information concerning the setting up and interpretation of therapeutic drug monitoring (TDM) for anti-epileptic drugs...
Keywords: anti-epileptic drugs, Review, therapeutic drug monitoring
11/2004 | Clinical Chemical Laboratory Medicine, Walter de GruyterOral fluid as a diagnostic tool
Technological advances over the past decades have enabled oral fluid to expand its usefulness in the diagnosis of disease, prediction of disease progression, monitoring of therapeutic drug levels and detection of illicit drugs...
Keywords: illicit drugs, oral fluid, saliva, therapeutic drug monitoring
11/2004 | Clinical Chemical Laboratory Medicine, Walter de GruyterComparison of serum digoxin concentration monitoring by fluorescence polarization immunoassay on the TDxFLx® and dry chemistry enzyme immunoassay on the Vitros 950
The aim of the study was to compare the results of digoxin assays performed using fluorescence polarization immunoassay (FPIA) on the TDxFLx® and a dry chemistry enzyme immunoassay (EIA) on the Vitros 950...
Keywords: digoxin, dry chemistry, enzyme immunoassay, fluorescence polarization immunoassay, therapeutic drug monitoring
08/2004 | Clinical Chemical Laboratory Medicine, Walter de GruyterQuantification of voriconazole in plasma by liquid chromatography-tandem mass spectrometry
A convenient liquid chromatography-tandem mass spectrometry method for the quantification of the triazole antifungal agent voriconazole in plasma samples is described...
Keywords: liquid chromatography-tandem mass spectrometry, Solid phase extraction, therapeutic drug monitoring, voriconazole
07/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterMethoden zur Bestimmung von Thrombininhibitoren / Methods for the determination of thrombin inhibitors
Thrombininhibitoren sind als Antikoagulans für spezielle Indikationen zur Therapie zugelassen...
Keywords: aktivierte partielle Thromboplastinzeit, chromogener Substrattest, Ecarin-Gerinnungszeit, therapeutisches Drugmonitoring, Thrombininhibitoren, activated partial thromboplastin time, chromogenic substrate assay, ecarin clotting time, therapeutic drug monitoring, Thrombin inhibitors
10/2006 | LaboratoriumsMedizin, Walter de GruyterMeasurement of mycophenolic acid in plasma or serum by a commercial enzyme inhibition technique in comparison with a high performance liquid chromatography method
Keywords: COBAS Integra, enzyme inhibition assay, high performance liquid chromatography (HPLC), mycophenolic acid, therapeutic drug monitoring
09/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter