Items for "TBX21 (T-box21) gene"

Association analysis of hepatitis virus B infection with haplotypes of the TBX21 gene promoter region in the Chinese population

Background: The T-box21 (TBX21) gene encodes the transcription factor T-bet (T-box expressed in T-cells), which influences naive T-lymphocyte development and has been implicated in the pathogenesis of many diseases.

Methods: We selected 208 hepatitis B patients and 213 healthy volunteers to examine whether polymorphisms or haplotypes of the TBX21 gene promoter were associated with hepatitis B virus (HBV) infection in the Chinese population...

Keywords: genetic susceptibility, haplotype, hepatitis B virus (HBV), promoter, TBX21 (T-box21) gene