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Items for "tacrolimus"

Therapeutic monitoring of immunosuppressant drugs. Where are we?

The emergence of specific immunosuppressive drugs (cyclosporine, tacrolimus, mycophenolate mofetil and sirolimus) during the last two decades has contributed dramatically to the success of organ transplantation...

Keywords: cyclosporine, mycophenolic acid, sirolimus, tacrolimus, therapeutic drug monitoring

11/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
The influence of genetic polymorphisms of cytochrome P450 3A5 and ABCB1 on starting dose- and weight-standardized tacrolimus trough concentrations after kidney transplantation in relation to renal function

Background: Cytochrome P450 3A5 (CYP3A5) and ABCB1 polymorphisms have been shown to influence tacrolimus (Tc) blood concentrations in the stable phase after organ transplantation...

Keywords: kidney transplantation, pharmacogenetics, renal function, tacrolimus

10/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter