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Items for "synovial fluid"

Examination of synovial fluid and serum following intravenous injections of hyaluronan for the treatment of osteoarthritis in dogs

A randomized, blinded, prospective clinical trial was performed to determine the effects of intravenous (IV) administration of hyaluronan sodium (HA) on serum glycosaminoglycans (GAG) concentrations, synovial fluid (SF) hyaluronan concentrations and viscosity in dogs treated for unilateral rupture of the cranial cruciate ligament...

Keywords: Hyaluronic acid, synovial fluid, Osteoarthritis

08/2005 | Veterinary and Comparative Orthopaedics and Traumatology, Schattauer
Matrix metalloproteinase and tissue inhibitor of metalloproteinase in serum and synovial fluid of osteoarthritic dogs

To better understand the mechanisms responsible for the pathological processes of osteoarthritis (OA) and topotentially identify a profile of changes that could bepredictive of early OA, matrix metalloproteinase-1(MMP-1) and tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) in the synovial fluid and serum ofnormal and osteoarthritic dogs were examined...

Keywords: Matrix metalloproteinase, synovial fluid, serum

00/0000 | Veterinary and Comparative Orthopaedics and Traumatology, Schattauer
Optimization of an enzymatic method for the determination of lysosomal N-acetyl-?-D-hexosaminidase and ?-glucuronidase in synovial fluid

Background: Our goal was to develop a suitably sensitive assay for N-acetyl-?-D-hexosaminidase (HEX) and ?-glucuronidase to allow their use as markers of joint diseases.

Methods: We optimized a spectrophotometric method for the determination of lysosomally derived HEX and ?-glucuronidase in synovial fluid on a microplate reader to improve its utility...

Keywords: ?-glucuronidase, Km, N-acetyl-?-D-hexosaminidase, rheumatoid arthritis, synovial fluid

08/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter