Vascular injury triggers endothelial exocytosis of granules, releasing pro-inflammatory and pro-thrombotic mediators into the blood...
Keywords: endothelial cell, Hydrogen Peroxide, nitric oxide, peroxynitrite, Platelet, reactive oxygen species, superoxide, Weibel-Palade bodies
10/2006 | Biological Chemistry, Walter de GruyterActive inflammatory leukocytes are a major endogenous source of reactive oxygen and nitrogen oxide species (RONS)...
Keywords: chemoprevention, co-culture, macrophage, mutagenesis, nitric oxide, phytochemicals, superoxide
04/2006 | Biological Chemistry, Walter de GruyterDespite substantial evidence indicating the association of hyperhomocysteinemia (hHcys) and end-stage renal disease (ESRD), the pathogenic role of increased plasma homocysteine (Hcys) levels in the progression of ESRD remains unclear...
Keywords: glomerular sclerosis, homocysteine, NADPH oxidase, Rac GTPase, superoxide
12/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter