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Items for "substrate specificity"

Specificity of human cathepsin S determined by processing of peptide substrates and MHC class II-associated invariant chain

Cathepsin S (CatS) is a lysosomal cysteine protease of the papain family, the members of which possess relatively broad substrate specificities...

Keywords: antigen processing, cathepsin S, electrospray mass spectrometry, invariant chain, MHC class II, substrate specificity

10/2006 | Biological Chemistry, Walter de Gruyter
The His-Pro-Phe motif of angiotensinogen is a crucial determinant of the substrate specificity of renin

The amino acid sequence His-Pro-Phe as N-terminal residues 6–8 of the natural renin substrate, angiotensinogen, is conserved among species...

Keywords: exosite, megsin, molecular anchor, renin-angiotensin system, renin inhibitor, substrate specificity

02/2007 | Biological Chemistry, Walter de Gruyter
Glutamic acid-141: a heme ‘bodyguard’ in anionic tobacco peroxidase

The role of the conserved glutamic acid residue in anionic plant peroxidases with regard to substrate specificity and stability was examined...

Keywords: expression, purification, radiation-induced inactivation, recombinant tobacco peroxidase, refolding, site-directed mutagenesis, substrate specificity

04/2007 | Biological Chemistry, Walter de Gruyter