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Items for "structure-activity relationship"

Limb girdle muscular dystrophy in a sibling pair with a homozygous Ser606Leu mutation in the alternatively spliced IS2 region of calpain 3

Previous family studies revealed a large number of calpain 3 (CAPN3) mutations that cause recessive forms of limb girdle muscular dystrophy (LGMD2A) with selective atrophy of the proximal limb muscles...

Keywords: linkage, missense mutation, molecular model, mutation analysis, Phenotype, structure-activity relationship

01/2005 | Biological Chemistry, Walter de Gruyter
Structure-activity relationships of cadinane-type sesquiterpene derivatives against wood-decay fungi

Cadinane-type sesquiterpenes have a wide spectrum of biological activity, but their use as wood preservatives and the structure-activity relationships of their derivatives have not yet been reported...

Keywords: cadinane-type sesquiterpene, ?-cadinol, 4?H-cadinan-10?-ol, 3?-ethoxy-T-muurolol, log P, 4?H-muurolan-10?-ol, structure-activity relationship, wood-decay fungi

11/2005 | Holzforschung, Walter de Gruyter