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Items for "Stroke"

Stroke: epidemiology, risk factors, and genetics

Stroke constitutes a major global challenge for health policy and healthcare economics. Reducing stroke burden requires extensive knowledge of risk factors and, if applicable, preventive control...

Keywords: Schlaganfall, Epidemiologie, Risikofaktoren, Genetik

01/2006 | Hämostaseologie, Schattauer
Stroke: causes and classification

Cerebrovascular disease is caused by ischaemic stroke, intracerebral haemorrhage, subarachnoidal haemorrhage or cerebral vein and sinus thrombosis...

Keywords: Schlaganfall, Ursachen, Klassifikation

01/2006 | Hämostaseologie, Schattauer
Endovascular therapy of stroke

Standard therapy of acute ischaemic stroke during the first three hours after symptom onset is intravenous thrombolysis...

Keywords: Schlaganfall, Thrombolyse

01/2006 | Hämostaseologie, Schattauer
Secondary prevention of stroke

Patients suffering a transient ischaemic attack (TIA) or ischaemic stroke (IS) have a high recurrence risk...

Keywords: Schlaganfall, Sekundärprävention, Thrombozytenfunktionshemmer

01/2006 | Hämostaseologie, Schattauer
A Scoring System for Ascertainment of Incident Stroke; the Risk Index Score (RISc)

Objectives: The main objective of this study was to develop and validate a computer-based statistical algorithm that could be translated into a simple scoring system in order to ascertain incident stroke cases using hospital admission medical records data. Methods: The Risk Index Score (RISc) algorithm was developed using data collected prospectively by the Brain Attack Surveillance in Corpus Christi (BASIC) project, 2000...

Keywords: Stroke, epidemiology, screening, surveillance, informatics

01/2006 | Methods of Information in Medicine, Schattauer
Two Models for Outcome Prediction A Comparison of Logistic Regression and Neural Networks

OBJECTIVES: Accurately predicting disease progress from a set of predictive variables is an important aspect of clinical work...

Keywords: artificial neural network, regression, benchmarking, Prognosis, Stroke

01/2006 | Methods of Information in Medicine, Schattauer
Enhanced platelet activation by prolactin in patients with ischemic stroke

Prolactin and leptin are newly recognised platelet co-stimulators due to potentiation of ADP-induced platelet aggregation...

Keywords: platelets, CD62p, Stroke, prolactin, leptin

07/2006 | Thrombosis and Haemostasis, Schattauer
Detection of brain injury by fatty acid-binding proteins

The rapid detection of brain injury (neuronal damage in general) is an important parameter in the management of cerebrovascular accidents, especially in hemorrhagic and/or ischemic events...

Keywords: brain injury, dementia, fatty acid-binding protein, heart-type fatty acid-binding protein (H-FABP), Ischemia, neurological disorders, Stroke

08/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
The significance of serum ?-glutamyltransferase in cardiovascular diseases

Since early after the introduction of serum ?-glutamyltransferase (GGT) in clinical practice as a reliable and widely employed laboratory test, epidemiological and prospective studies have repeatedly shown that this activity possesses a prognostic value for morbidity and mortality...

Keywords: atherosclerosis, glutathione, myocardial infarction, serum ?-glutamyltransferase, Stroke

10/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Methylenetetrahydrofolate reductase gene A222V polymorphism and risk of ischemic stroke

The 5,10-methylenetetrahydrofolate reductase (MTHFR) gene 677C?T polymorphism causes an A222V amino acid change which affects MTHFR enzyme activity and can increase homocysteine, a vascular disease risk factor...

Keywords: elderly, folate, methylenetetrahydrofolate reductase (MTHFR), mutation, Polymorphism, Stroke

12/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Matrix metalloproteinases and their inhibitors in different acute stroke subtypes

The aim of the study was to determine serum levels of selected matrix metalloproteinases (MMPs) and their natural inhibitors (TIMPs) in the acute phase of different stroke types subdivided according to the Oxfordshire Community Stroke Project (OCSP) classification and the possibility of discriminating stroke types according to their levels...

Keywords: matrix metalloproteinases, Stroke, tissue inhibitor of metalloproteinases

04/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Polymorphisms of the inflammatory system and risk of ischemic cerebrovascular events

Background: Chronic and acute infections are associated with an increased risk of stroke...

Keywords: infection, inflammation, interleukins, Polymorphism, Stroke, tumor necrosis factor

08/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Association of vitamin B12, folate and homocysteine with functional and pathological characteristics of the elderly in a mountainous village in Sicily

Background: Homocysteine is associated with age, folate and vitamin B12...

Keywords: aging, folate, peripheral arteriopathy, Stroke, vitamin B12

02/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Monitoring of platelet activation and function after ischemic stroke Thrombozytenaktivität und -funktion nach ischämischem zerebralem Insult

Assessment of platelet activation after ischemic stroke could be clinically valuable if platelet markers existed that predict the risk of recurrent events and reflect the effect of antiplatelet therapy...

Keywords: Sekundärprophylaxe, Schlaganfall, Thrombozyten, Thrombozyten-aggregationshemmer, Thrombozytendiagnostik

10/2005 | LaboratoriumsMedizin, Walter de Gruyter