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Items for "statins"

Immunization of LDL receptor-deficient mice with & 2 -glycoprotein 1 or human serum albumin induces a more inflammatory phenotype in atherosclerotic plaques

Antiphospholipid antibodies are a risk factor for venous and arterial thrombosis and may contribute to the development of atherosclerosis...

Keywords: Antiphospholipid antibodies, atherosclerosis, β2-glycoprotein 1, immunization, statins

01/2007 | Thrombosis and Haemostasis, Schattauer
Familial hypercholesterolemia and response to statin therapy according to LDLR genetic background

Familial hypercholesterolemia is an autosomal dominant disease defined at the molecular level mainly by the presence of mutations in the low-density lipoprotein receptor gene and is characterized by elevated low-density lipoprotein cholesterol, tendon xanthomas and increased risk of early cardiovascular disease...

Keywords: cholesterol, familial hypercholesterolemia, HMG-CoA, low-density lipoprotein receptor (LDL-R), statins, therapy

08/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter