Staphylococcal adhesins mediate attachment to matrix proteins and endothelial cells in vitro, yet, their role in primary adherence to the physiologic vessel wall has not been studied in vivo, and complex endocarditis models yielded ambiguous results...
Keywords: Staphylococcus aureus, endothelium, intravital fluorescence microscopy, fibronectin binding protein A, adherence
08/2006 | Thrombosis and Haemostasis, SchattauerSurface molecules of Staphylococcus aureus are involved in the colonization of vascular endothelium which is a crucial primary event in the pathogenesis of infective endocarditis (IE)...
Keywords: Staphylococcus aureus, endocarditis, Coagulation, fibronectin binding protein A, endothelium, activation
04/2007 | Thrombosis and Haemostasis, SchattauerOf seven human cystatins investigated, none inhibited the cysteine proteases staphopain A and B secreted by the human pathogen
Keywords: cysteine peptidases, protease inhibitors, Staphylococcus aureus, virulence factors
04/2007 | Biological Chemistry, Walter de Gruyter