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Items for "Staphylococcus aureus"

Fibronectin binding proteins contribute to the adherence of Staphylococcus aureus to intact endothelium in vivo

Staphylococcal adhesins mediate attachment to matrix proteins and endothelial cells in vitro, yet, their role in primary adherence to the physiologic vessel wall has not been studied in vivo, and complex endocarditis models yielded ambiguous results...

Keywords: Staphylococcus aureus, endothelium, intravital fluorescence microscopy, fibronectin binding protein A, adherence

08/2006 | Thrombosis and Haemostasis, Schattauer
Fibronectin-binding proteins and clumping factor A in Staphylococcus aureus experimental endocarditis: FnBPA is sufficient to activate human endothelial cells

Surface molecules of Staphylococcus aureus are involved in the colonization of vascular endothelium which is a crucial primary event in the pathogenesis of infective endocarditis (IE)...

Keywords: Staphylococcus aureus, endocarditis, Coagulation, fibronectin binding protein A, endothelium, activation

04/2007 | Thrombosis and Haemostasis, Schattauer
Down-regulation of human extracellular cysteine protease inhibitors by the secreted staphylococcal cysteine proteases, staphopain A and B

Of seven human cystatins investigated, none inhibited the cysteine proteases staphopain A and B secreted by the human pathogen Staphylococcus aureus...

Keywords: cysteine peptidases, protease inhibitors, Staphylococcus aureus, virulence factors

04/2007 | Biological Chemistry, Walter de Gruyter