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Items for "SPINK5"

Inhibition of human kallikreins 5 and 7 by the serine protease inhibitor lympho-epithelial Kazal-type inhibitor (LEKTI)

LEKTI is a 120-kDa protein that plays an important role in skin development, as mutations affecting LEKTI synthesis underlie Netherton syndrome, an inherited skin disorder producing severe scaling...

Keywords: desquamation, Netherton syndrome, SPINK5, standard mechanism inhibitor

11/2005 | Biological Chemistry, Walter de Gruyter