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Items for "sphingomyelinase"

Hydrophobic bile salts trigger ceramide formation through endosomal acidification

Hydrophobic bile salts activate NADPH oxidase through a ceramide- and PKC?-dependent pathway as an important upstream event of bile salt-induced hepatocyte apoptosis...

Keywords: bile acids, CD95, chloride, FAS, oxidative stress, p47phox, sphingomyelinase

02/2007 | Biological Chemistry, Walter de Gruyter