Protease nexin-1 (PN-1) is a non-circulating pericellular serpin expressed by vascular cells. PN-1 inhibits different proteases but when associated with glycosaminoglycans, its activity is mainly directed towards thrombin...
Keywords: Protease nexin-1, thrombin, smooth muscle cells, polysaccharides, fucoidans
00/0000 | Thrombosis and Haemostasis, SchattauerVascular calcification is characterized by cellular transdifferentiation and expression of bone-related matrix proteins that result in the presence of bone-like structures in the vascular wall...
Keywords: Cbfa1, interleukin-4, osteoprotegerin, smooth muscle cells, vascular calcification
04/2006 | Thrombosis and Haemostasis, SchattauerWe have recently drawn attention to the fact that most non-peptide antagonists of the kinin B1 receptor reported so far are structurally related, possessing the core motif phenyl-SO2-NR-(spacer2–4)-CO-NRR...
Keywords: bradyzide, LF16-0687, rabbit aorta, radioligand binding assay, smooth muscle cells
02/2006 | Biological Chemistry, Walter de Gruyter