Items for "small-molecule inhibitor of p-selectin"

Resolution of venous thrombosis using a novel oral small-molecule inhibitor of P-selectin (PSI-697) without anticoagulation

P-selectin inhibition has been shown to decrease thrombogenesis in multiple animal species. In this study, we show that a novel oral small-molecule inhibitor of P-selectin, PSI-697, promotes thrombus resolution and decreases inflammation in a baboon model of venous thrombosis...

Keywords: Deep venous thrombosis, thrombus resolution, small-molecule inhibitor of p-selectin, inflammation, Animal models