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Items for "sirolimus"

Therapeutic monitoring of immunosuppressant drugs. Where are we?

The emergence of specific immunosuppressive drugs (cyclosporine, tacrolimus, mycophenolate mofetil and sirolimus) during the last two decades has contributed dramatically to the success of organ transplantation...

Keywords: cyclosporine, mycophenolic acid, sirolimus, tacrolimus, therapeutic drug monitoring

11/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Evaluation of an immunoassay of whole blood sirolimus in pediatric transplant patients in comparison with high-performance liquid chromatography/tandem mass spectrometry

Background: Sirolimus is widely used as an immunosuppressant, along with calcineurin inhibitors...

Keywords: immunoassay, microparticle enzyme immunoassay, Mass spectrometry, sirolimus

04/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
A rapid liquid chromatography-tandem mass spectrometry analysis of whole blood sirolimus using turbulent flow technology for online extraction

Background: Sirolimus is an immunosuppressant used in solid organ transplantation...

Keywords: liquid chromatography, Mass spectrometry, sirolimus, turbulent flow

11/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter