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Items for "shedding"

GPCR-induced migration of breast carcinoma cells depends on both EGFR signal transactivation and EGFR-independent pathways

The epidermal growth factor receptor (EGFR) plays a key role in the regulation of important cellular processes under normal and pathophysiological conditions such as cancer...

Keywords: ADAM, breast cancer, cross-talk, HB-EGF, shedding, sphingosine kinase (SPHK)

09/2005 | Biological Chemistry, Walter de Gruyter
Effects of elastase and cathepsin G on the levels of membrane and soluble TNF?

Neutrophil elastase (NE) and cathepsin G (CG), the proteolytic enzymes localized in azurophil granules of neutrophils (PMN), are involved in PMN responses to various stimuli...

Keywords: cathepsin G, elastase, inflammation, neutrophil, shedding, tumor necrosis factor ? (TNF?)

08/2005 | Biological Chemistry, Walter de Gruyter