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Items for "sex hormone-binding globulin"

Evaluation of a new automated electrochemiluminescent sex hormone-binding globulin (SHBG) immunoassay

Serum sex hormone-binding globulin (SHBG) regulates the cellular bioavailability of SHBG-bound steroid hormones...

Keywords: immunoassay, sex hormone-binding globulin

01/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
A simple method for estimating equilibrium constants for serum testosterone binding resulting in an optimal free testosterone index for use in elderly men

An algorithm was developed to evaluate equilibrium constants for testosterone (Te) and sex hormone-binding globulin (SHBG) or albumin from serum free testosterone (FTe) measurements performed in a panel of 30 healthy elderly men by means of a near-reference method, i.e., symmetric dialysis (affinity constants: SHBG-Te, 1.13×10 9 L/mol; albumin-Te, 4.4×10 4 L/mol)...

Keywords: dialysis, Equilibrium constant, free testosterone, sex hormone-binding globulin

06/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Biochemical reference intervals for sex hormones with a new AutoDelfia method in aged men

Background: Our aim was to establish sex hormone reference intervals measured with a new AutoDelfia immunoassay method for aged men free of medication and/or conditions known to influence sex hormone levels.

Methods: The reference population consisted of 466 individuals between 64 and 97 years (mean 72 years) and a mean body mass index (BMI) of 26.9 kg/m2.

Results and conclusions: Because age correlated significantly with most sex hormones studied, we calculated reference intervals for three age groups (64–69, 70–74 and ?75 years)...

Keywords: androgens, elderly, estrogens, men, reference interval, sex hormone-binding globulin

02/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter