AIMS: Definition of the regional pattern of dopamine transporter (DAT) dysfunction in advanced Parkinson's disease (PD) and evaluation of a potential correlation between DAT binding and symptoms; elucidation of the role of DAT imaging in the differential diagnosis of PD and multiple system atrophy (MSA); assessment and comparison of serotonin transporter (SERT) binding in PD and MSA. METHODS: [123I]-CIT SPECT was performed in 14 patients with advanced PD, 10 with moderate MSA and 20 healthy persons...
Keywords: Dopamintransporter, Serotonintransporter, Morbus Parkinson, Multisystematrophie, SPECT, beta-CIT
01/2003 | Nuklearmedizin, Schattauer