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selenoproteins
Items for "selenoproteins"
Selenium in mammalian spermiogenesis
The role of the trace element selenium in maintaining male fertility is reviewed with special emphasis on the importance of selenoprotein P and GPx4 in spermiogenesis...
Keywords: male fertility, moonlighting protein, phospholipid hydroperoxide glutathione peroxidase (GPx4), selenium, selenoproteins, spermatogenesis
01/2007 | Biological Chemistry, Walter de GruyterActivation of the glutathione peroxidase 2 (GPx2) promoter by ?-catenin
GPx2, formerly called gastrointestinal GPx, is highly expressed in the proliferative area of the intestinal crypt-to-villus axis and in Paneth cells...
Keywords: ß-catenin, carcinogenesis, gastrointestinal glutathione peroxidase, GPx2, proliferation, selenoproteins, transcriptional, regulation
01/2007 | Biological Chemistry, Walter de GruyterSelenium in chemistry and biochemistry in comparison to sulfur
What makes selenoenzymes – seen from a chemists view – so special that they cannot be substituted by just more analogous or adapted sulfur proteins? This review compiles and compares physicochemical properties of selenium and sulfur, synthetic routes to selenocysteine (Sec) and its peptides, and comparative studies of relevant thiols and selenols and their (mixed) dichalcogens, required to understand the special role of selenium in selenoproteins on the atomic molecular level...
Keywords: disulfide/diselenide/selenenylsulfide interchange, enzyme mechanisms, selenocysteine, selenoproteins, Synthesis
01/2007 | Biological Chemistry, Walter de GruyterDie medizinische Bedeutung von Selen / The clinical relevance of selenium
Selen ist ein essentielles Spurenelement, das für viele Organfunktionen bedeutsam ist...
Keywords: Selen, Selenbedarf, Selenoenzyme, Selen-Wirkungen, selenium, selenium effects, selenium requirement, selenoproteins
08/2006 | LaboratoriumsMedizin, Walter de Gruyter