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Items for "selenoprotein"

Resveratrol modulates mRNA transcripts of genes related to redox metabolism and cell proliferation in non-small-cell lung carcinoma cells

Resveratrol is a polyphenolic chemopreventive agent that has been shown to influence cellular redox reactions...

Keywords: A549 cells, antioxidant capacity, cell cycle arrest, chemoprevention, glutathione peroxidase, selenoprotein

02/2007 | Biological Chemistry, Walter de Gruyter
The physiological role of phospholipid hydroperoxide glutathione peroxidase in mammals

The redox enzyme phospholipid hydroperoxide glutathione peroxidase (PHGPx) has emerged as one of the most significant selenoenzymes in mammals, corroborated by early embryonic lethality of PHGPx null mice...

Keywords: glutathione peroxidase 4, lipid peroxidation, selenoprotein, spermatogenesis, thiol peroxidase

01/2007 | Biological Chemistry, Walter de Gruyter
B- and T-cell-specific inactivation of thioredoxin reductase 2 does not impair lymphocyte development and maintenance

Thioredoxin reductases (Txnrds) are a group of selenoenzymes participating in cellular redox regulation...

Keywords: CD4-Cre, CD19-Cre, conditional knockout, lymphocyte, selenoprotein

01/2007 | Biological Chemistry, Walter de Gruyter
Effect of selenium on thioredoxin reductase activity in Txnrd1 or Txnrd2 hemizygous mice

Thioredoxin reductase 1 (Txnrd1) and Thioredoxin reductase 2 (Txnrd2) are selenoproteins whose expression and function depends on adequate supply with the trace element selenium (Se)...

Keywords: enzymatic activity, haploid insufficiency, hemizygosity, selenium deficiency, selenoprotein

01/2007 | Biological Chemistry, Walter de Gruyter