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Items for "selenium"

Inverse association between serum selenium concentrations and parameters of immune activation in patients with cardiac disorders

Background: As a component of the enzyme glutathione peroxidase, the essential trace element selenium contributes to the reduction of peroxides...

Keywords: cardiac disorders, immune activation, neopterin, oxidative stress, selenium, tryptophan degradation

05/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Direct determination of selenium in human serum by inductively coupled plasma-collision cell-mass spectrometry

Background: Selenium status in humans depends on nutritional intake...

Keywords: hexapole collision cell, human serum, inductively coupled plasma mass spectrometry (ICP-MS), sample dilution, selenium

07/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Selenium in mammalian spermiogenesis

The role of the trace element selenium in maintaining male fertility is reviewed with special emphasis on the importance of selenoprotein P and GPx4 in spermiogenesis...

Keywords: male fertility, moonlighting protein, phospholipid hydroperoxide glutathione peroxidase (GPx4), selenium, selenoproteins, spermatogenesis

01/2007 | Biological Chemistry, Walter de Gruyter
The molecular biology of glutathione peroxidase 4: from genomic structure to developmental expression and neural function

Selenoproteins have been recognized as modulators of brain function and signaling. Phospholipid hydroperoxide glutathione peroxidase (GPx4/PHGPx) is a unique member of selenium-dependent glutathione peroxidases in mammals with a pivotal role for brain development and function...

Keywords: Apoptosis, embryogenesis, excitotoxicity, glial cells, oxidative stress, phosphoinositides, selenium

01/2007 | Biological Chemistry, Walter de Gruyter
Posttranslational processing of selenoprotein P: implications of glycosylation for its utilisation by target cells

Selenoprotein P (SeP) is a highly glycosylated plasma protein containing up to 10 selenocysteine residues...

Keywords: calcium, Ea.hy926 endothelial cell, glutathione peroxidase, monensin, selenium, tunicamycin

01/2007 | Biological Chemistry, Walter de Gruyter
Bedeutung von Chrom, Kupfer, Selen und Zink bei Diabetes mellitus Typ 1 und Typ 2 mit Folgeerkrankungen / Importance of chromium, copper, selenium and zinc in diabetes mellitus type 1 and type 2 with late disease

Zusammenfassung

Chrom aktiviert die Wirkung von Insulin. Bei Typ-1- und Typ-2-Diabetikern reflektierten verminderte Chromgehalte in Leukozyten eine verminderte Chromversorgung...

Keywords: Arteriosklerose, Chrom, Diabetes mellitus Typ 1 und Typ 2, Folgeerkrankungen, Kupfer, Mangel, Mikroangiopathie, Nephropathie, Neuropathie, Selen, Spurenelemente, Supplementation, Versorgung, Zink, arteriosclerosis, chromium, copper, deficiency, diabetes mellitus type 1 and type 2, late disease, microangiopathy, nephropathy, neuropathy, selenium, supply, trace elements, Zinc

08/2006 | LaboratoriumsMedizin, Walter de Gruyter
Die medizinische Bedeutung von Selen / The clinical relevance of selenium

Zusammenfassung

Selen ist ein essentielles Spurenelement, das für viele Organfunktionen bedeutsam ist...

Keywords: Selen, Selenbedarf, Selenoenzyme, Selen-Wirkungen, selenium, selenium effects, selenium requirement, selenoproteins

08/2006 | LaboratoriumsMedizin, Walter de Gruyter