To date, no effective adjuvant drug preventing the aggressive spread of tumour cells in late stages of cancer disease or at the time-point of primary tumour removal is available...
Keywords: Tiermodelle, Serinproteasen, Proteaseinhibitoren, Metastasierung, Screening, Lymphom, Fibrosarkom
01/2007 | Hämostaseologie, SchattauerAs a follow-up to our preceding paper, we attempted to extract features of health risk progression for diabetes in Sequential Multi Layered Perceptron (SMLP) via inverse processing of the learned structure...
Keywords: Precursors, diabetes, time-varying, SMLP, screening, health risk appraisal
01/2004 | Methods of Information in Medicine, SchattauerOBJECTIVES: The next generation of high energy physics (HEP) experiments requires a GRID approach to a distributed computing system: the key concept is the Virtual ORGANISATION (VO), a group of distributed users with a common goal and the will to share their resources. METHODS: A similar approach, applied to a group of hospitals that joined the GPCALMA project (Grid Platform for Computer Assisted Library for MAmmography), will allow common screening programs for early diagnosis of breast and, in the future, lung cancer...
Keywords: Grid, mammogram, screening, virtual organization
01/2005 | Methods of Information in Medicine, SchattauerOBJECTIVES: This study assessed the relationships between cancer screening beliefs (perceived pros, cons, and susceptibility) and reactions (acceptance, selfefficacy, intention to purchase) to an innovative home-administered kit (HAK) for fecal occult blood test (FOBT) among Chinese worksite population. METHODS: A total of 450 Chinese people aged 40 and older were recruited from ten worksites in Taiwan (2002), with response rate of 83% (375/450). RESULTS: All the belief scales of cancer screening in general showed good internal consistency (Cronbach alphas >0.70)...
Keywords: Colorectal neoplasm, screening, occult blood, self efficacy, Chinese
01/2005 | Methods of Information in Medicine, SchattauerOBJECTIVES: Discussion of different error concepts relevant to microarray experiments. Review of some commonly used multiple testing procedures...
Keywords: Familywise error rate, false discovery rate, error concepts, screening
01/2005 | Methods of Information in Medicine, SchattauerObjectives: The main objective of this study was to develop and validate a computer-based statistical algorithm that could be translated into a simple scoring system in order to ascertain incident stroke cases using hospital admission medical records data. Methods: The Risk Index Score (RISc) algorithm was developed using data collected prospectively by the Brain Attack Surveillance in Corpus Christi (BASIC) project, 2000...
Keywords: Stroke, epidemiology, screening, surveillance, informatics
01/2006 | Methods of Information in Medicine, SchattauerThis paper reviews chromatographic screening procedures for simultaneous detection of several drug classes relevant to clinical and forensic toxicology or doping control in urine or blood using gas chromatography-mass spectrometry (GC-MS), liquid chromatography coupled with a diode-array detector (LC-DAD) or a mass spectrometer (LC-MS)...
Keywords: chromatography, diode-array detection, drugs, Mass spectrometry, screening
11/2004 | Clinical Chemical Laboratory Medicine, Walter de GruyterGestational diabetes mellitus (GDM) is defined as carbohydrate intolerance during pregnancy...
Keywords: gestational diabetes, pregnancy, screening
09/2004 | Clinical Chemical Laboratory Medicine, Walter de GruyterThe aim of this study was to compare the diagnostic utility of complexed prostate-specific antigen (cPSA) with total PSA (tPSA) in screening for prostate cancer...
Keywords: cancer of the prostate, complexed/free prostate-specific antigen ratio, complexed prostate-specific antigen, free prostate-specific antigen, prostate-specific antigen, screening
09/2004 | Clinical Chemical Laboratory Medicine, Walter de GruyterPhenylketonuria is an inherited metabolic disease, which is characterized by an increased level of serum phenylalanine...
Keywords: Guthrie, phenylalanine, phenylketonuria, screening
01/2006 | Clinical Chemical Laboratory Medicine, Walter de GruyterWorldwide, allergic diseases are increasing in prevalence and incidence. Early assessment of the immunoglobulin E (IgE) sensitisation status has a major impact on clinical outcome and selection of therapeutic options...
Keywords: allergy, CAP classes, screening, specific IgE
09/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterKeywords: aged, holotranscobalamin, homocysteine, renal impairment, screening, vitamin B12 deficiency
02/2007 | Clinical Chemical Laboratory Medicine, Walter de GruyterStatus and school achievement of 129 children born in Hessen between 1988 and 1992 and notified by a repeatedly elevated concentration of TSH in neonatal screening were evaluated...
Keywords: congenital hypothyroidism, etiology, familial disposition, psychomotor and educational development, screening
12/2005 | Journal of Perinatal Medicine, Walter de GruyterKeywords: ascorbic acid, gestational diabetes, glycosuria, pregnancy, screening
08/2006 | Journal of Perinatal Medicine, Walter de GruyterKeywords: diabetes, hCG, PAPP-A, preeclampsia, pregnancy outcome, screening, SGA
04/2006 | Journal of Perinatal Medicine, Walter de GruyterDie diagnostischen Kriterien - und damit auch die Prävalenz - wurden im Laufe der Zeit unterschiedlich definiert...
Keywords: C-peptide, Diabetes mellitus, diagnostische Kriterien, HbA1c, Prävalenz, Proinsulin, screening, diagnostic criteria, prevalence
08/2004 | LaboratoriumsMedizin, Walter de Gruyter