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Items for "screening"

Anti-metastatic effects of serine protease inhibitors: animal models for analysis

To date, no effective adjuvant drug preventing the aggressive spread of tumour cells in late stages of cancer disease or at the time-point of primary tumour removal is available...

Keywords: Tiermodelle, Serinproteasen, Proteaseinhibitoren, Metastasierung, Screening, Lymphom, Fibrosarkom

01/2007 | Hämostaseologie, Schattauer
Application of a Prediction Model for Identification of Individuals at Diabetic Risk

As a follow-up to our preceding paper, we attempted to extract features of health risk progression for diabetes in Sequential Multi Layered Perceptron (SMLP) via inverse processing of the learned structure...

Keywords: Precursors, diabetes, time-varying, SMLP, screening, health risk appraisal

01/2004 | Methods of Information in Medicine, Schattauer
GPCALMA: a Grid-based Tool for Mammographic Screening

OBJECTIVES: The next generation of high energy physics (HEP) experiments requires a GRID approach to a distributed computing system: the key concept is the Virtual ORGANISATION (VO), a group of distributed users with a common goal and the will to share their resources. METHODS: A similar approach, applied to a group of hospitals that joined the GPCALMA project (Grid Platform for Computer Assisted Library for MAmmography), will allow common screening programs for early diagnosis of breast and, in the future, lung cancer...

Keywords: Grid, mammogram, screening, virtual organization

01/2005 | Methods of Information in Medicine, Schattauer
Cancer Screening Beliefs and Reactions to an Innovative Colorectal Cancer Screening Kit among Chinese Worksite Population

OBJECTIVES: This study assessed the relationships between cancer screening beliefs (perceived pros, cons, and susceptibility) and reactions (acceptance, selfefficacy, intention to purchase) to an innovative home-administered kit (HAK) for fecal occult blood test (FOBT) among Chinese worksite population. METHODS: A total of 450 Chinese people aged 40 and older were recruited from ten worksites in Taiwan (2002), with response rate of 83% (375/450). RESULTS: All the belief scales of cancer screening in general showed good internal consistency (Cronbach alphas >0.70)...

Keywords: Colorectal neoplasm, screening, occult blood, self efficacy, Chinese

01/2005 | Methods of Information in Medicine, Schattauer
Multiplicity Issues in Microarray Experiments

OBJECTIVES: Discussion of different error concepts relevant to microarray experiments. Review of some commonly used multiple testing procedures...

Keywords: Familywise error rate, false discovery rate, error concepts, screening

01/2005 | Methods of Information in Medicine, Schattauer
A Scoring System for Ascertainment of Incident Stroke; the Risk Index Score (RISc)

Objectives: The main objective of this study was to develop and validate a computer-based statistical algorithm that could be translated into a simple scoring system in order to ascertain incident stroke cases using hospital admission medical records data. Methods: The Risk Index Score (RISc) algorithm was developed using data collected prospectively by the Brain Attack Surveillance in Corpus Christi (BASIC) project, 2000...

Keywords: Stroke, epidemiology, screening, surveillance, informatics

01/2006 | Methods of Information in Medicine, Schattauer
Position of chromatographic techniques in screening for detection of drugs or poisons in clinical and forensic toxicology and/or doping control

This paper reviews chromatographic screening procedures for simultaneous detection of several drug classes relevant to clinical and forensic toxicology or doping control in urine or blood using gas chromatography-mass spectrometry (GC-MS), liquid chromatography coupled with a diode-array detector (LC-DAD) or a mass spectrometer (LC-MS)...

Keywords: chromatography, diode-array detection, drugs, Mass spectrometry, screening

11/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
The clinical impact of screening for gestational diabetes

Gestational diabetes mellitus (GDM) is defined as carbohydrate intolerance during pregnancy...

Keywords: gestational diabetes, pregnancy, screening

09/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
The measurement of complexed prostate-specific antigen has a better performance than total prostate-specific antigen

The aim of this study was to compare the diagnostic utility of complexed prostate-specific antigen (cPSA) with total PSA (tPSA) in screening for prostate cancer...

Keywords: cancer of the prostate, complexed/free prostate-specific antigen ratio, complexed prostate-specific antigen, free prostate-specific antigen, prostate-specific antigen, screening

09/2004 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Quantitative bacterial micro-assay for rapid detection of serum phenylalanine on dry blood-spots: application in phenylketonuria screening

Phenylketonuria is an inherited metabolic disease, which is characterized by an increased level of serum phenylalanine...

Keywords: Guthrie, phenylalanine, phenylketonuria, screening

01/2006 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Diagnostic and analytical performance of a screening panel for allergy

Worldwide, allergic diseases are increasing in prevalence and incidence. Early assessment of the immunoglobulin E (IgE) sensitisation status has a major impact on clinical outcome and selection of therapeutic options...

Keywords: allergy, CAP classes, screening, specific IgE

09/2005 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Renal impairment compromises the use of total homocysteine and methylmalonic acid but not total vitamin B12 and holotranscobalamin in screening for vitamin B12 deficiency in the aged

Background: Vitamin B12 deficiency and renal impairment are common in the aged, and therefore the screening test for vitamin B12 deficiency should not be affected by renal function...

Keywords: aged, holotranscobalamin, homocysteine, renal impairment, screening, vitamin B12 deficiency

02/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Neonatal screening for congenital hypothyroidism in Hessen, Germany: efficiency of the screening program and school achievement of 129 children at an age of 8–12 years

Status and school achievement of 129 children born in Hessen between 1988 and 1992 and notified by a repeatedly elevated concentration of TSH in neonatal screening were evaluated...

Keywords: congenital hypothyroidism, etiology, familial disposition, psychomotor and educational development, screening

12/2005 | Journal of Perinatal Medicine, Walter de Gruyter
Accuracy and influence of ascorbic acid on glucose-test with urine dip sticks in prenatal care

Objective: In Germany, urine analysis with dip sticks are used for screening of gestational diabetes...

Keywords: ascorbic acid, gestational diabetes, glycosuria, pregnancy, screening

08/2006 | Journal of Perinatal Medicine, Walter de Gruyter
The efficacy of first-trimester PAPP-A and free ?hCG levels for predicting adverse pregnancy outcome

Objective: To determine whether first-trimester measurements of maternal serum PAPP-A and free ?hCG levels were associated with adverse pregnancy outcomes.

Study Design: First trimester maternal serum free ?hCG and PAPP-A were measured in 490 singleton pregnancies...

Keywords: diabetes, hCG, PAPP-A, preeclampsia, pregnancy outcome, screening, SGA

04/2006 | Journal of Perinatal Medicine, Walter de Gruyter
Laboratoriumsdiagnostik bei Diabetes mellitus/Laboratory diagnostics in patients with diabetes mellitus

Zusammenfassung

Zusammenfassung Diabetes mellitus umfasst eine Gruppe von metabolischen Störungen, welche durch eine Hyperglykämie als Folge von Störungen der Insulinsekretion, der Insulinaktivität oder von beidem charakterisiert sind.

Die diagnostischen Kriterien - und damit auch die Prävalenz - wurden im Laufe der Zeit unterschiedlich definiert...

Keywords: C-peptide, Diabetes mellitus, diagnostische Kriterien, HbA1c, Prävalenz, Proinsulin, screening, diagnostic criteria, prevalence

08/2004 | LaboratoriumsMedizin, Walter de Gruyter