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Items for "SARS-coronavirus 3CL protease"

Development of a red-shifted fluorescence-based assay for SARS-coronavirus 3CL protease: identification of a novel class of anti-SARS agents from the tropical marine sponge Axinella corrugata

SARS-coronavirus (SARS-CoV) encodes a main protease, 3CLpro, which plays an essential role in the viral life cycle and is currently the prime target for discovering new anti-coronavirus agents...

Keywords: fluorescence-based protease assay, internally quenched fluorogenic peptide substrate, SARS-coronavirus 3CL protease, viral protease, viral protease inhibitor

08/2006 | Biological Chemistry, Walter de Gruyter