Items for "saposin-homologous domain"

Functional characterization of the postulated intramolecular sphingolipid activator protein domain of human acid sphingomyelinase

Degradation of membrane-bound sphingomyelin to phosphorylcholine and ceramide is catalyzed by the water-soluble lysosomal acid sphingomyelinase (A-SMase)...

Keywords: acid sphingomyelinase, saposin-homologous domain, site-directed mutagenesis, water-lipid interface