Alkylphosphocholines (APCs) represent a new and very encouraging class of antitumour agents that have also been shown to induce apoptosis in tumour cells, but their exact mode of action has still not been elucidated...
Keywords: Bid, caspase activation, mitochondria, mitochondrial membrane permeabilisation, S-NC-2
03/2005 | Biological Chemistry, Walter de Gruyter