In eukaryotic cells, double-stranded RNA is degraded to 21mers and triggers RNA interference...
Keywords: gene regulation, genome analysis, pattern search, RNAi, siRNAs
10/2004 | Biological Chemistry, Walter de GruytermicroRNAs (miRNAs) form an evolutionarily conserved and highly abundant class of non-coding RNAs that are 21–24 nucleotides (nt) in length...
Keywords: Argonaute proteins, double-stranded RNA, microRNA, posttranscriptional gene silencing, RNAi, translational regulation
12/2005 | Biological Chemistry, Walter de GruytermicroRNAs (miRNAs) are non-coding RNAs that target specific mRNAs. They have been shown to control many biological processes including cancer pathogenesis...
Keywords: Cancer, kallikrein, KLK, microRNA, miRNA, RNAi, siRNA, tumor markers
06/2008 | Biological Chemistry, Walter de GruytermicroRNAs (miRNAs) are a recently discovered class of small non-coding RNAs that regulate gene expression...
Keywords: bioinformatics, kallikrein, KLK, microRNA, RNAi, target validation
06/2008 | Biological Chemistry, Walter de Gruyter