Rituximab is a chimeric anti-CD20 monoclonal antibody active against normal and malignant B cells which has proven to be effective in the therapy of CD-20 positive lymphomas...
Keywords: Rituximab, inhibitor, coagulation disorders
08/2006 | Thrombosis and Haemostasis, SchattauerTreatment of relapsed or refractory autoimmune mediated haemolytic syndromes, such as autoimmune haemolytic anaemia (AIHA) and thrombotic thrombocytopenic purpura (TTP), represents a therapeutic challenge...
Keywords: Rituximab, TTP, AIHA
00/0000 | Thrombosis and Haemostasis, SchattauerRituximab was successively labeled with [ 67Ga]-gallium chloride. The macrocyclic bifunctional chelating agent, N-succinimidyl-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA-NHS) was prepared at 25 °C using DOTA, N-hydroxy succinimide (NHS) in CH2Cl2...
Keywords: Rituximab, Gallium-67, Radiolabeling, Quality Control, DOTA
03/2008 | Radiochimica Acta, Oldenbourg Wissenschaftsverlag