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Items for "Rituximab"

The efficacy of rituximab in the treatment of inhibitor-associated hemostatic disorders

Rituximab is a chimeric anti-CD20 monoclonal antibody active against normal and malignant B cells which has proven to be effective in the therapy of CD-20 positive lymphomas...

Keywords: Rituximab, inhibitor, coagulation disorders

08/2006 | Thrombosis and Haemostasis, Schattauer
Addition of rituximab to standard therapy improves response rate and progression-free survival in relapsed or refractory thrombotic thrombocytopenic purpura and autoimmune haemolytic anaemia

Treatment of relapsed or refractory autoimmune mediated haemolytic syndromes, such as autoimmune haemolytic anaemia (AIHA) and thrombotic thrombocytopenic purpura (TTP), represents a therapeutic challenge...

Keywords: Rituximab, TTP, AIHA

00/0000 | Thrombosis and Haemostasis, Schattauer
Preparation, quality control and biodistribution studies of [67Ga]-DOTA-anti-CD20

Rituximab was successively labeled with [ 67Ga]-gallium chloride. The macrocyclic bifunctional chelating agent, N-succinimidyl-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA-NHS) was prepared at 25 °C using DOTA, N-hydroxy succinimide (NHS) in CH2Cl2...

Keywords: Rituximab, Gallium-67, Radiolabeling, Quality Control, DOTA

03/2008 | Radiochimica Acta, Oldenbourg Wissenschaftsverlag