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Items for "Rho"

Asef is a Cdc42-specific guanine nucleotide exchange factor

Asef is a member of the Dbl-family of guanine nucleotide exchange factors (GEFs) with a proposed specificity for the small GTPase Rac1...

Keywords: APC, ASEF, Cdc42, exchange factor, GEF, GTPase, Rac, Rho

01/2007 | Biological Chemistry, Walter de Gruyter
p190-RhoGAP as an integral component of the Tiam1/Rac1-induced downregulation of Rho

The Rho family of small GTPases plays a central role in intracellular signal transduction, particularly in reorganization of the actin cytoskeleton...

Keywords: GTPase, p115-RhoGEF, p190-RhoGAP, PDZ-RhoGEF, Rac, Rho, Tiam1

03/2006 | Biological Chemistry, Walter de Gruyter