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Items for "rFVIIa"

Bleeding after cardiac surgery: the role of recombinant factor VIIa

Cardiac surgery carries a remarkable risk of blood loss requiring transfusion of blood products. Moreover, severe bleeding necessitating reoperation occurs in 35% of patients according to international studies...

Keywords: Herzchirurgie, rFVIIa, Herz-Lungen-Maschine, Blutung

01/2006 | Hämostaseologie, Schattauer
Tissue factor-enriched vesicles are taken up by platelets and induce platelet aggregation in the presence of factor VIIa

We investigated the interactions of vesicles containing human tissue factor (TF) with platelets and evaluated responses induced by rFVIIa using standard aggregometry, ultrastructural and flow-cytometry techniques...

Keywords: platelets, Tissue factor, vesicles, traffic, rFVIIa

00/0000 | Thrombosis and Haemostasis, Schattauer