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Items for "reverse hybridization"

Validation of a reverse-hybridization StripAssay for the simultaneous analysis of common α-thalassemia point mutations and deletions

Background: α-Thalassemia is a worldwide disease and considered to be a major public health problem in countries within the so-called thalassemia belt...

Keywords: -globin, genotyping, reverse hybridization, thalassemia

05/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Determination of the hepatitis C virus subtype: comparison of sequencing and reverse hybridization assays

Background: Hepatitis C virus (HCV) genotyping and accurate subtyping is becoming increasingly relevant to epidemiological studies, clinical management, pathogenicity, and vaccine development.

Methods: The TRUGENE® HCV 5?NC Genotyping Kit, the new VERSANT® HCV Genotype 2.0 Assay (LiPA), and a new laboratory-developed HCV NS5b sequencing assay designed for automated sequencing of the HCV NS5b region were used...

Keywords: hepatitis C virus, NS5b, reverse hybridization, sequencing, subtype

02/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter