The reference change value, defined as RCV=1.96×2 1/2×(s I 2+s A 2) 1/2, where s I is within-subject biological variation and s A is analytical variation, has been used for many years to take clinical decisions in patient monitoring...
Keywords: between-subject biological variation, cut-off, index of individuality, population-based reference interval, power function, reference change value, within-subject biological variation
04/2005 | Clinical Chemical Laboratory Medicine, Walter de GruyterKeywords: adiponectin, biovariation, diurnal changes, frozen storage, post-prandial period, reference change value
10/2006 | Clinical Chemical Laboratory Medicine, Walter de GruyterKeywords: biological variation, laboratory quality specifications, parathyroid hormone, reference change value
10/2008 | Clinical Chemical Laboratory Medicine, Walter de Gruyter