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Items for "reactive oxygen species"

Ceramides induce programmed cell death in Arabidopsis cells in a calcium-dependent manner

While the role of C2-ceramide in the induction of programmed cell death (PCD) in animal systems has been well documented, little is known of its role in plant cells...

Keywords: Apoptosis, calcium signalling, reactive oxygen species

02/2005 | Biological Chemistry, Walter de Gruyter
N-Ethylmaleimide-sensitive factor: a redox sensor in exocytosis

Vascular injury triggers endothelial exocytosis of granules, releasing pro-inflammatory and pro-thrombotic mediators into the blood...

Keywords: endothelial cell, Hydrogen Peroxide, nitric oxide, peroxynitrite, Platelet, reactive oxygen species, superoxide, Weibel-Palade bodies

10/2006 | Biological Chemistry, Walter de Gruyter
Regulatory effects of the mitochondrial energetic status on mitochondrial p66Shc

p66Shc promotes apoptosis and controls the intracellular redox balance...

Keywords: Apoptosis, mitochondria, reactive oxygen species

10/2006 | Biological Chemistry, Walter de Gruyter
Risk factors and mechanisms of hepatocarcinogenesis with special emphasis on alcohol and oxidative stress

Hepatocellular cancer is the fifth most frequent cancer in men and the eighth in women worldwide...

Keywords: Acetaldehyde, cytochrome P4502E1, hepatitis, methyl group transfer, reactive oxygen species, retinoids

04/2006 | Biological Chemistry, Walter de Gruyter
Relationship between neurological outcome and early oxidative changes in erythrocytes in head injury patients

Background: Experimental data indicate that destructive oxidative events reach their peak within the first 24 h after trauma in head injury (HI) and that brain damage occurring due to this impact can be the cause of death or irreversible permanent disabilities in affected patients.

Methods: Venous blood samples were obtained from 50 HI patients within 24 h of trauma onset and from 30 age- and sex-matched normal controls (NC)...

Keywords: erythrocytes, glutathione, lipid peroxidation, outcome, reactive oxygen species

05/2007 | Clinical Chemical Laboratory Medicine, Walter de Gruyter
Adrenodoxin (Adx) and CYP11A1 (P450scc) induce apoptosis by the generation of reactive oxygen species in mitochondria

Mitochondrial cytochrome P450 systems are an indispensable component of mammalian steroid biosynthesis; they catalyze regio- and stereo-specific steroid hydroxylations and consist of three protein entities: adrenodoxin reductase (AdR), adrenodoxin (Adx), and a mitochondrial cytochrome P450 enzyme, e.g., CYP11A1 (P450 side chain cleavage, P450scc)...

Keywords: adrenodoxin, Apoptosis, CYP11A1, cytochrome P450, electron transfer chain, mitochondria, reactive oxygen species, steroid hydroxylation

05/2005 | Biological Chemistry, Walter de Gruyter
Incinerator fly ash provokes alteration of redox equilibrium and liberation of arachidonic acid in vitro

Numerous epidemiological studies have associated exposure to ambient particulate matter (PM) with pulmonary and cardiovascular health effects...

Keywords: cyclooxygenase-2, incinerator fly ash, macrophages, oxidative stress, particulate matter, reactive oxygen species

10/2006 | Biological Chemistry, Walter de Gruyter